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3 INDICATIONS VOQUEZNA® (vonoprazan) is indicated for the healing of all grades of Erosive Esophagitis in adults Read More

VOQUEZNA achieved strong healing rates in all grades of Erosive GERD

Met the primary efficacy endpoint for healing: noninferiority vs lansoprazole

PRIMARY NONINFERIORITY ENDPOINT:
COMPLETE HEALING RATES BY WEEK 8

Bar graph shows that for the primary non-inferiority endpoint of complete healing of Erosive GERD by Week 8, 93% of patients on VOQUEZNA® (vonoprazan) achieved complete healing vs 85 % on lansoprazole

93% of VOQUEZNA
patients achieved healing

Observed healing rates in all grades of Erosive GERD at Week 2

SECONDARY ENDPOINT: COMPLETE HEALING RATES AT WEEK 2 FOR ALL GRADES1,2,*

secondary endpoint complete healing rates at week 2 - 74% in the VOQUEZNA® (vonoprazan) 20mg arm vs. 68% in the Lansoprazole 30mg arm

*Endpoint not tested for statistical significance due to prespecified hierarchy and does not provide evidence of superiority.2

Observed healing rates in patients with moderate-to-severe Erosive GERD by Week 8

SECONDARY ENDPOINT: COMPLETE HEALING RATES BY WEEK 8 FOR GRADES C/D1,2,*,†

Secondary endpoint bar graph shows 92% of patients treated with VOQUEZNA® (vonoprazan) and 72% of patients treated with lansoprazole achieved complete healing by Week 8 for grades C/D

*Endpoint not tested for statistical significance due to prespecified hierarchy and does not provide evidence of superiority.

†Severity of the disease was classified based on the LA Classification Grading System (Grades A through D), with mild Erosive Esophagitis being Grades A or B and severe Erosive Esophagitis being Grades C or D.1,2

Superior healing rates vs lansoprazole in moderate-to-severe Erosive GERD at Week 2

SECONDARY SUPERIORITY ENDPOINT: COMPLETE HEALING RATES AT WEEK 2 FOR GRADES C/D1,2,*

Bar graph of secondary endpoint shows 70% of patients treated with VOQUEZNA® (vonoprazan) and 53% of patient treated with lansoprazole achieved complete healing at Week 2 for grades C/D

*Severity of the disease was classified based on the LA Classification Grading System (Grades A through D), with mild Erosive Esophagitis being Grades A or B and severe Erosive Esophagitis being Grades C or D.1,2

Hear from Brooks D. Cash, MD, on efficacy and safety

Learn more about the VOQUEZNA efficacy results seen in pHalcon-EE

See a video about VOQUEZNA efficacy results in Non-Erosive GERD.

SEE SAFETY DATASEE MAINTENANCE RESULTS
SEE
NON-EROSIVE
GERD DATA